Automated assessment of bone changes in cross-sectional micro-CT studies of murine experimental osteoarthritis
Fig 2
Bland-Altman plots to determine the agreement between the measurements in automatically and manually segmented subchondral bone compartments.
The difference between measurements using automated and manual segmentation was plotted against the average for the subchondral bone plate (A) volume and (B) thickness, and trabecular (C) total volume, (D) bone volume and (E) BV/TV, (n = 24 in which the measurements in the medial and lateral aspects of the plateau for both right and left legs were pooled together). The mean (solid line) and the 95% limits of agreement (-1.96SD, +1.96SD, indicated by the area shaded in blue between the dashed lines) for each microstructural parameter are reported in the plots.