A new NASH model in aged mice with rapid progression of steatohepatitis and fibrosis

Xuecheng Li; Yi Lu; Xiaoshuang Liang; Xiaofei Zhou; Dirui Li; Zan Zhang; Yunchao Niu; Shuaishuai Liu; Ling Ye; Rufeng Zhang

doi:10.1371/journal.pone.0286257

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Open Access

Peer-reviewed

Research Article

A new NASH model in aged mice with rapid progression of steatohepatitis and fibrosis

Xuecheng Li ,

Contributed equally to this work with: Xuecheng Li, Yi Lu, Xiaoshuang Liang

Roles Project administration

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Yi Lu ,

Contributed equally to this work with: Xuecheng Li, Yi Lu, Xiaoshuang Liang

Roles Project administration

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Xiaoshuang Liang ,

Contributed equally to this work with: Xuecheng Li, Yi Lu, Xiaoshuang Liang

Roles Project administration

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Xiaofei Zhou,

Roles Conceptualization

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Dirui Li,

Roles Conceptualization, Writing – review & editing

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Zan Zhang,

Roles Methodology

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Yunchao Niu,

Roles Methodology, Project administration

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Shuaishuai Liu,

Roles Project administration

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Ling Ye,

Roles Project administration

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China
⨯
Rufeng Zhang

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

* E-mail: zhangrf1992@163.com

Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd, Beijing, Daxing District, China

https://orcid.org/0000-0001-7379-6597

⨯

A new NASH model in aged mice with rapid progression of steatohepatitis and fibrosis

Xuecheng Li,
Yi Lu,
Xiaoshuang Liang,
Xiaofei Zhou,
Dirui Li,
Zan Zhang,
Yunchao Niu,
Shuaishuai Liu,
Ling Ye,
Rufeng Zhang

Published: May 25, 2023
https://doi.org/10.1371/journal.pone.0286257

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Fatty liver
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Steatosis
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