The clinical value of proneural, classical and mesenchymal protein signatures in WHO 2021 adult-type diffuse lower-grade gliomas

• Anna Dénes ,

  Contributed equally to this work with: Anna Dénes, Thomas Olsson Bontell

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: anna.denes@gu.se

  Affiliation Department of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  https://orcid.org/0000-0003-0187-4423

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• Thomas Olsson Bontell ,

  Contributed equally to this work with: Anna Dénes, Thomas Olsson Bontell

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden, Department of Physiology, Institute of Neuroscience and Physiology, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden

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• Hanna Barchéus,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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• Sandra Ferreyra Vega,

  Roles Formal analysis, Investigation, Resources, Writing – review & editing

  Affiliations Department of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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• Helena Carén,

  Roles Resources, Writing – review & editing

  Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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• Cecilia Lindskog,

  Roles Resources, Writing – review & editing

  Affiliation Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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• Asgeir S. Jakola,

  Roles Formal analysis, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Department of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Department of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden

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• Anja Smits

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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