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Open Access
Peer-reviewed
Research Article
Real-world performance of SARS-Cov-2 serology tests in the United States, 2020
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Carla V. Rodriguez-Watson ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: crodriguezwatson@reaganudall.org
Affiliation Reagan-Udall Foundation for the FDA, Washington, District of Columbia, United States of America
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Anthony M. Louder ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Methodology, Writing – review & editing
Affiliation Aetion, New York, New York, United States of America
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Carly Kabelac ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Resources, Writing – review & editing
Affiliation Aetion, New York, New York, United States of America
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Christopher M. Frederick ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Regenstrief Institute, Indianapolis, Indiana, United States of America
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Natalie E. Sheils ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Optum Labs, Minnetonka, Minnesota, United States of America
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Elizabeth H. Eldridge ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Health Catalyst, Salt Lake City, Utah, United States of America
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Nancy D. Lin ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Health Catalyst, Salt Lake City, Utah, United States of America
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Benjamin D. Pollock ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Mayo Clinic, Rochester, Minnesota, United States of America
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Jennifer L. Gatz ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Regenstrief Institute, Indianapolis, Indiana, United States of America
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Shaun J. Grannis ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliations Regenstrief Institute, Indianapolis, Indiana, United States of America, Department of Family Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Rohit Vashisht ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, California, United States of America
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Kanwal Ghauri ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Software, Writing – original draft, Writing – review & editing
Affiliation Reagan-Udall Foundation for the FDA, Washington, District of Columbia, United States of America
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Camille Knepper ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Mayo Clinic, Rochester, Minnesota, United States of America
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Sandy Leonard ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation HealthVerity, Philadelphia, Pennsylvania, United States of America
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Peter J. Embi ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Methodology, Resources, Writing – review & editing
Affiliation Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Garrett Jenkinson ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Mayo Clinic, Rochester, Minnesota, United States of America
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Reyna Klesh ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation HealthVerity, Philadelphia, Pennsylvania, United States of America
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Omai B. Garner ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, UCLA Medical Center, Los Angeles, California, United States of America
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Ayan Patel ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America
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Lisa Dahm ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America
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Aiden Barin ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America
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Dan M. Cooper ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliations Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America, Pediatric Exercise and Genomics Research Center, University of California Irvine School of Medicine, Irvine, California, United States of America
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Tom Andriola ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliations Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America, Office of Data and Information Technology, University of California, Irvine, Irvine, California, United States of America
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Carrie L. Byington ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America
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Bridgit O. Crews ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, California, United States of America
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Atul J. Butte ,
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliations Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, California, United States of America, Center for Data-Driven Insights and Innovation, University of California Health, Oakland, California, United States of America
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Jeff Allen
Contributed equally to this work with: Carla V. Rodriguez-Watson, Anthony M. Louder, Carly Kabelac, Christopher M. Frederick, Natalie E. Sheils, Elizabeth H. Eldridge, Nancy D. Lin, Benjamin D. Pollock, Jennifer L. Gatz, Shaun J. Grannis, Rohit Vashisht, Kanwal Ghauri, Camille Knepper, Sandy Leonard, Peter J. Embi, Garrett Jenkinson, Reyna Klesh, Omai B. Garner, Ayan Patel, Lisa Dahm, Aiden Barin, Dan M. Cooper, Tom Andriola, Carrie L. Byington, Bridgit O. Crews, Atul J. Butte, Jeff Allen
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation Friends of Cancer Research, Washington, District of Columbia, United States of America
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Real-world performance of SARS-Cov-2 serology tests in the United States, 2020
- Carla V. Rodriguez-Watson,
- Anthony M. Louder,
- Carly Kabelac,
- Christopher M. Frederick,
- Natalie E. Sheils,
- Elizabeth H. Eldridge,
- Nancy D. Lin,
- Benjamin D. Pollock,
- Jennifer L. Gatz,
- Shaun J. Grannis
- Published: February 3, 2023
- https://doi.org/10.1371/journal.pone.0279956