A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression

• JooYeon Jhun ,

  Contributed equally to this work with: JooYeon Jhun, Hyun Sik Na

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Validation, Writing – original draft

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Hyun Sik Na ,

  Contributed equally to this work with: JooYeon Jhun, Hyun Sik Na

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Keun-Hyung Cho,

  Roles Data curation, Investigation, Methodology, Validation

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Jiyoung Kim,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Young-Mee Moon,

  Roles Data curation, Project administration

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Seung Yoon Lee,

  Roles Data curation, Methodology

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Jeong Su Lee,

  Roles Formal analysis, Methodology

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• A. Ram Lee,

  Roles Data curation, Formal analysis, Methodology

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  ⨯
• Seok Jung Kim,

  Roles Resources, Supervision

  Affiliation Department of Orthopedic Surgery, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

  ⨯
• Mi-La Cho ,

  Roles Conceptualization, Project administration, Supervision

  * E-mail: iammila@catholic.ac.kr (M-LC); rapark@catholic.ac.kr (S-HP)

  Current address: Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea; Department of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Republic of Korea

  ¶‡ These authors also contributed equally to this work

  Affiliation The Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, South Korea

  https://orcid.org/0000-0001-5715-3989

  ⨯
• Sung-Hwan Park

  Roles Funding acquisition, Resources, Supervision

  * E-mail: iammila@catholic.ac.kr (M-LC); rapark@catholic.ac.kr (S-HP)

  ¶‡ These authors also contributed equally to this work

  Affiliation Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

  ⨯