Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants’ spike protein–an in silico analysis

• Suman Pokhrel ,

  Contributed equally to this work with: Suman Pokhrel, Benjamin R. Kraemer, Lucia Lee

  Roles Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States of America

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• Benjamin R. Kraemer ,

  Contributed equally to this work with: Suman Pokhrel, Benjamin R. Kraemer, Lucia Lee

  Roles Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States of America

  https://orcid.org/0000-0003-0375-4652

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• Lucia Lee ,

  Contributed equally to this work with: Suman Pokhrel, Benjamin R. Kraemer, Lucia Lee

  Roles Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States of America

  ⨯
• Kate Samardzic,

  Roles Visualization, Writing – review & editing

  Affiliation Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States of America

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• Daria Mochly-Rosen

  Roles Conceptualization, Supervision

  * E-mail: mochly@stanford.edu

  Affiliation Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States of America

  https://orcid.org/0000-0002-6691-8733

  ⨯