Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response

Ji Eun Kim; Jin Ju Park; Mi Rim Lee; Jun Young Choi; Bo Ram Song; Ji Won Park; Mi Ju Kang; Hong Joo Son; Jin Tae Hong; Dae Youn Hwang

doi:10.1371/journal.pone.0215205

Loading metrics

Open Access

Peer-reviewed

Research Article

Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response

Ji Eun Kim,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Jin Ju Park,

Roles Formal analysis, Investigation, Project administration

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Mi Rim Lee,

Roles Formal analysis, Investigation, Methodology, Software

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Jun Young Choi,

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Bo Ram Song,

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Ji Won Park,

Roles Data curation, Methodology

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Mi Ju Kang,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Hong Joo Son,

Roles Writing – review & editing

Affiliation Department of Life Science and Environmental Biochemistry, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea
⨯
Jin Tae Hong,

Roles Supervision, Writing – review & editing

Affiliation College of Pharmacy, Chungbuk National University, Chungju, Korea
⨯
Dae Youn Hwang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: dyhwang@pusan.ac.kr

Affiliation Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Korea

http://orcid.org/0000-0002-5144-1725

⨯

Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response

Ji Eun Kim,
Jin Ju Park,
Mi Rim Lee,
Jun Young Choi,
Bo Ram Song,
Ji Won Park,
Mi Ju Kang,
Hong Joo Son,
Jin Tae Hong,
Dae Youn Hwang

Published: April 12, 2019
https://doi.org/10.1371/journal.pone.0215205

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Constipation
Is the Subject Area "Constipation" applicable to this article?

Thanks for your feedback.
Muscarinic acetylcholine receptors
Is the Subject Area "Muscarinic acetylcholine receptors" applicable to this article?

Thanks for your feedback.
Colon
Is the Subject Area "Colon" applicable to this article?

Thanks for your feedback.
Endoplasmic reticulum stress response
Is the Subject Area "Endoplasmic reticulum stress response" applicable to this article?

Thanks for your feedback.
Alzheimer's disease
Is the Subject Area "Alzheimer's disease" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Mucin
Is the Subject Area "Mucin" applicable to this article?

Thanks for your feedback.
Secretion
Is the Subject Area "Secretion" applicable to this article?

Thanks for your feedback.