Sera selected from national STI surveillance system shows Chlamydia trachomatis PgP3 antibody correlates with time since infection and number of previous infections

Paula B. Blomquist; Stephanie J. Mighelsen; Gillian Wills; Eleanor McClure; Anthony E. Ades; Daphne Kounali; J. Kevin Dunbar; Myra O. McClure; Kate Soldan; Sarah C. Woodhall; Patrick Horner

doi:10.1371/journal.pone.0208652

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Peer-reviewed

Research Article

Sera selected from national STI surveillance system shows Chlamydia trachomatis PgP3 antibody correlates with time since infection and number of previous infections

Paula B. Blomquist ,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Visualization, Writing – original draft, Writing – review & editing

* E-mail: paula.blomquist@phe.gov.uk

Affiliations Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, Public Health England, London, United Kingdom, Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England and in collaboration with London School of Hygiene & Tropical Medicine, London, United Kingdom, Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom

http://orcid.org/0000-0002-3962-4211

⨯
Stephanie J. Mighelsen,

Roles Investigation, Validation, Writing – review & editing

Affiliations Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, Public Health England, London, United Kingdom, Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England and in collaboration with London School of Hygiene & Tropical Medicine, London, United Kingdom, Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom
⨯
Gillian Wills,

Roles Conceptualization, Investigation, Methodology, Project administration, Resources

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Eleanor McClure,

Roles Investigation

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Anthony E. Ades,

Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

Affiliations Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom, Population Health Science Institute, University of Bristol, Bristol, United Kingdom
⨯
Daphne Kounali,

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

Affiliations Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom, Population Health Science Institute, University of Bristol, Bristol, United Kingdom

http://orcid.org/0000-0002-6392-6690

⨯
J. Kevin Dunbar,

Roles Supervision, Writing – review & editing

Affiliations Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, Public Health England, London, United Kingdom, Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England and in collaboration with London School of Hygiene & Tropical Medicine, London, United Kingdom, Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom
⨯
Myra O. McClure,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Kate Soldan,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliations Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, Public Health England, London, United Kingdom, Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England and in collaboration with London School of Hygiene & Tropical Medicine, London, United Kingdom, Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom
⨯
Sarah C. Woodhall,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliations Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, Public Health England, London, United Kingdom, Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England and in collaboration with London School of Hygiene & Tropical Medicine, London, United Kingdom, Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom
⨯
Patrick Horner

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

Affiliations Health Protection Research Unit in Evaluation of Interventions at University of Bristol in partnership with Public Health England, Bristol, United Kingdom, Population Health Science Institute, University of Bristol, Bristol, United Kingdom
⨯

Sera selected from national STI surveillance system shows Chlamydia trachomatis PgP3 antibody correlates with time since infection and number of previous infections

Paula B. Blomquist,
Stephanie J. Mighelsen,
Gillian Wills,
Eleanor McClure,
Anthony E. Ades,
Daphne Kounali,
J. Kevin Dunbar,
Myra O. McClure,
Kate Soldan,
Sarah C. Woodhall

Published: December 17, 2018
https://doi.org/10.1371/journal.pone.0208652

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