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Open Access
Peer-reviewed
Research Article
Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial
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Menaka Pai ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: mpai@mcmaster.ca
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Hamilton Regional Laboratory Medicine Program, Hamilton, Canada, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada
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Neill K. J. Adhikari,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Canada, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
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Marlies Ostermann,
Roles Conceptualization, Writing – review & editing
Affiliation Department of Critical Care, Guys and St Thomas Hospital, London, England
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Diane Heels-Ansdell,
Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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James D. Douketis,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Yoanna Skrobik,
Roles Writing – review & editing
Affiliation Department of Medicine, Hôpital Maisonneuve Rosemont, Montréal, Canada
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Ismael Qushmaq,
Roles Conceptualization, Writing – review & editing
Affiliation Department of Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia
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Maureen Meade,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Gordon Guyatt,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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William Geerts,
Roles Conceptualization, Writing – review & editing
Affiliation Department of Medicine, University of Toronto, Toronto, Canada
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Michael W. Walsh,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Mark A. Crowther,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Hamilton Regional Laboratory Medicine Program, Hamilton, Canada, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada
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Jan O. Friedrich,
Roles Conceptualization, Writing – review & editing
Affiliations Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada, Department of Medicine, University of Toronto, Toronto, Canada
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Lisa Burry,
Roles Conceptualization, Writing – review & editing
Affiliation Mount Sinai Hospital, Toronto, Canada
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Rinaldo Bellomo,
Roles Conceptualization, Writing – review & editing
Affiliation Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia
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Nilton Brandão da Silva,
Roles Conceptualization, Writing – review & editing
Affiliation Moinhos de Vento Hospital, Porto Alegre, Brazil
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Rubens Costa Filho,
Roles Conceptualization, Writing – review & editing
Affiliation Pró Cardíaco Hospital, PROCEP, Rio de Janeiro, Brazil
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Michael J. Cox,
Roles Conceptualization, Writing – review & editing
Affiliation St. John's Mercy Medical Center, St. Louis, Missouri, United States of America
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Suzana Alves Silva,
Roles Conceptualization, Writing – review & editing
Affiliation Pró Cardíaco Hospital, PROCEP, Rio de Janeiro, Brazil
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Deborah J. Cook,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Medicine, McMaster University, Hamilton, Canada, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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on behalf of the PROTECT (Prophylaxis for Thromboembolism in Critical Care Trial) Investigators
¶Membership of the PROTECT Investigators is provided in the Acknowledgments.
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Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial
- Menaka Pai,
- Neill K. J. Adhikari,
- Marlies Ostermann,
- Diane Heels-Ansdell,
- James D. Douketis,
- Yoanna Skrobik,
- Ismael Qushmaq,
- Maureen Meade,
- Gordon Guyatt,
- William Geerts
- Published: June 1, 2018
- https://doi.org/10.1371/journal.pone.0198285