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Open Access
Peer-reviewed
Research Article
Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms
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Madhura Panse,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliations University of Tübingen, Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Tübingen, Germany, German Center for Diabetes Research (DZD), München-Neuherberg, Germany
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Oliver Kluth,
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliations German Center for Diabetes Research (DZD), München-Neuherberg, Germany, German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Experimental Diabetology, Potsdam-Rehbruecke, Germany
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Estela Lorza-Gil,
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliations University of Tübingen, Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Tübingen, Germany, German Center for Diabetes Research (DZD), München-Neuherberg, Germany, Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen (IDM), Tübingen, Germany
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Gabriele Kaiser,
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliations University of Tübingen, Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Tübingen, Germany, German Center for Diabetes Research (DZD), München-Neuherberg, Germany, Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen (IDM), Tübingen, Germany
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Eckhard Mühlbauer,
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliations German Center for Diabetes Research (DZD), München-Neuherberg, Germany, German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Experimental Diabetology, Potsdam-Rehbruecke, Germany
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Annette Schürmann,
Roles Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing
Affiliations German Center for Diabetes Research (DZD), München-Neuherberg, Germany, German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Experimental Diabetology, Potsdam-Rehbruecke, Germany
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Hans-Ulrich Häring,
Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing
Affiliations University of Tübingen, Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Tübingen, Germany, German Center for Diabetes Research (DZD), München-Neuherberg, Germany, Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen (IDM), Tübingen, Germany
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Susanne Ullrich ,
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: susanne.ullrich@med.uni-tuebingen.de
Affiliations University of Tübingen, Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Tübingen, Germany, German Center for Diabetes Research (DZD), München-Neuherberg, Germany, Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen (IDM), Tübingen, Germany
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Felicia Gerst
Roles Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliations University of Tübingen, Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Tübingen, Germany, German Center for Diabetes Research (DZD), München-Neuherberg, Germany, Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen (IDM), Tübingen, Germany
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Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms
- Madhura Panse,
- Oliver Kluth,
- Estela Lorza-Gil,
- Gabriele Kaiser,
- Eckhard Mühlbauer,
- Annette Schürmann,
- Hans-Ulrich Häring,
- Susanne Ullrich,
- Felicia Gerst
- Published: May 29, 2018
- https://doi.org/10.1371/journal.pone.0198016