Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor

• Olga Gorelenkova Miller,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Kyle S. Cole,

  Roles Data curation, Methodology

  Affiliation Department of Chemistry, Boston College, Chestnut Hill, Massachusetts, United States of America

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• Corey C. Emerson,

  Roles Data curation, Formal analysis, Visualization

  Affiliation Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Dharmaraja Allimuthu,

  Roles Data curation, Methodology, Validation

  Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Marcin Golczak,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Visualization

  Affiliations Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America, Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Phoebe L. Stewart,

  Roles Funding acquisition, Methodology, Resources, Supervision

  Affiliations Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America, Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Eranthie Weerapana,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision

  Affiliation Department of Chemistry, Boston College, Chestnut Hill, Massachusetts, United States of America

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• Drew J. Adams,

  Roles Conceptualization, Methodology, Resources, Supervision

  Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America

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• John J. Mieyal

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: jjm5@cwru.edu

  Affiliations Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America, Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

  http://orcid.org/0000-0002-8957-6334

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