An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers

• Sophia E. Airhart,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Current address: Department of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, United States of America

  Affiliation Division of Cardiology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

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• Laura M. Shireman,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutics, University of Washington School of Pharmacy, Seattle, Washington, United States of America

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• Linda J. Risler,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Pharmaceutics, University of Washington School of Pharmacy, Seattle, Washington, United States of America

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• Gail D. Anderson,

  Roles Conceptualization, Formal analysis, Validation, Writing – review & editing

  Affiliation Department of Pharmacy, University of Washington School of Pharmacy, Seattle, Washington, United States of America

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• G. A. Nagana Gowda,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliations Northwest Metabolomics Research Center, Department of Anesthesiology & Pain Medicine; University of Washington, Seattle, Washington, United States of America, Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine; University of Washington, Seattle, Washington, United States of America

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• Daniel Raftery,

  Roles Methodology, Supervision, Visualization, Writing – review & editing

  Affiliations Northwest Metabolomics Research Center, Department of Anesthesiology & Pain Medicine; University of Washington, Seattle, Washington, United States of America, Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine; University of Washington, Seattle, Washington, United States of America

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• Rong Tian,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine; University of Washington, Seattle, Washington, United States of America

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• Danny D. Shen,

  Roles Formal analysis, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmaceutics, University of Washington School of Pharmacy, Seattle, Washington, United States of America, Department of Pharmacy, University of Washington School of Pharmacy, Seattle, Washington, United States of America

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• Kevin D. O’Brien

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Writing – original draft, Writing – review & editing

  * E-mail: cardiac@uw.edu

  Affiliation Division of Cardiology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

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