Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

• Ayal B. Gussow ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

  * E-mail: ayal.gussow@gmail.com (ABG); dg2875@cumc.columbia.edu (DBG)

  Affiliations Program in Computational Biology and Bioinformatics, Duke University, Durham, NC, United States of America, Institute for Genomic Medicine, Columbia University, New York, NY, United States of America

  http://orcid.org/0000-0002-0142-6084

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• Brett R. Copeland,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Institute for Genomic Medicine, Columbia University, New York, NY, United States of America

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• Ryan S. Dhindsa,

  Roles Conceptualization, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Institute for Genomic Medicine, Columbia University, New York, NY, United States of America

  http://orcid.org/0000-0002-8965-0813

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• Quanli Wang,

  Roles Conceptualization, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Institute for Genomic Medicine, Columbia University, New York, NY, United States of America

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• Slavé Petrovski,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Institute for Genomic Medicine, Columbia University, New York, NY, United States of America, Department of Medicine, The University of Melbourne, Austin Health and Royal Melbourne Hospital, Melbourne, Victoria, Australia

  http://orcid.org/0000-0002-1527-961X

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• William H. Majoros,

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliations Program in Computational Biology and Bioinformatics, Duke University, Durham, NC, United States of America, Center for Genomic and Computational Biology, Duke University, Durham, NC, United States of America

  http://orcid.org/0000-0001-7284-9335

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• Andrew S. Allen,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biostatistics and Bioinformatics, Duke University, Durham NC, United States of America

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• David B. Goldstein

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: ayal.gussow@gmail.com (ABG); dg2875@cumc.columbia.edu (DBG)

  Affiliation Institute for Genomic Medicine, Columbia University, New York, NY, United States of America

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