A Feasibility Study of Quantifying Longitudinal Brain Changes in Herpes Simplex Virus (HSV) Encephalitis Using Magnetic Resonance Imaging (MRI) and Stereology

• Sylviane Defres ,

  * E-mail: sdefres@liverpool.ac.uk

  Affiliations Clinical Infection, microbiology and immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom, Tropical and Infectious diseases Unit, Liverpool and Broadgreen University Hospital Trust, Liverpool, United Kingdom, NIHR HPRU in Emerging and Zoonotic Infections, University of Liverpool, Institute of infection and Global Health, Waterhouse Building, Liverpool, United Kingdom

  http://orcid.org/0000-0002-4729-7505

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• Simon S. Keller,

  Affiliations The Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom, The Department of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool, Liverpool, United Kingdom

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• Kumar Das,

  Affiliation The Department of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool, Liverpool, United Kingdom

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• Rishma Vidyasagar,

  Affiliations Florey Institute of Neuroscience and mental health, Heidelberg, Victoria, Australia, Department of Anatomy and Neuroscience, University of Melbourne, Victoria, Australia

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• Laura M. Parkes,

  Affiliation Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Girvan Burnside,

  Affiliation The department of Biostatistics, Institute of translational medicine, University of Liverpool, Liverpool, United Kingdom

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• Michael Griffiths,

  Affiliations Clinical Infection, microbiology and immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom

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• Michael Kopelman,

  Affiliation Institute of Psychiatry, Kings College London, London, United Kingdom

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• Neil Roberts,

  Affiliation Medical Physics and Imaging Science, University of Edinburgh, Edinburgh, United Kingdom

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• Tom Solomon,

  Affiliations Clinical Infection, microbiology and immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom, NIHR HPRU in Emerging and Zoonotic Infections, University of Liverpool, Institute of infection and Global Health, Waterhouse Building, Liverpool, United Kingdom, The Department of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool, Liverpool, United Kingdom

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• On behalf of ENCEPH UK study group

  ¶Membership of the ENCEPH-UK Study group is provided in the Acknowledgments.

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