Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization

• Mohun Ramratnam ,

  Contributed equally to this work with: Mohun Ramratnam, Guy Salama

  Affiliations Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison, WI, United States of America, Cardiology Section, Medical Service, William. S. Middleton Memorial Veterans Hospital, Madison, WI, United States of America, UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Guy Salama ,

  Contributed equally to this work with: Mohun Ramratnam, Guy Salama

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Ravi K. Sharma,

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• David Wen Rui Wang,

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Stephen H. Smith,

  Affiliation Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Sanjay K. Banerjee,

  Current address: Translational Health Science and Technology Institute, Gurgaon, India

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Xueyin N. Huang,

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Lindsey M. Gifford,

  Affiliations Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America, Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, United States of America

  ⨯
• Michele L. Pruce,

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Bethann E. Gabris,

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Samir Saba,

  Affiliation UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Sanjeev G. Shroff,

  Affiliation Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America

  ⨯
• Ferhaan Ahmad

  * E-mail: ferhaan-ahmad@uiowa.edu

  Affiliations UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America, Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, United States of America

  ⨯