1,25-Dihydroxyvitamin D Modulates Antibacterial and Inflammatory Response in Human Cigarette Smoke-Exposed Macrophages

Nele Heulens; Hannelie Korf; Carolien Mathyssen; Stephanie Everaerts; Elien De Smidt; Christophe Dooms; Jonas Yserbyt; Conny Gysemans; Ghislaine Gayan-Ramirez; Chantal Mathieu; Wim Janssens

doi:10.1371/journal.pone.0160482

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Open Access

Peer-reviewed

Research Article

1,25-Dihydroxyvitamin D Modulates Antibacterial and Inflammatory Response in Human Cigarette Smoke-Exposed Macrophages

Nele Heulens,

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Hannelie Korf,

Affiliation Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Carolien Mathyssen,

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Stephanie Everaerts,

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Elien De Smidt,

Affiliation Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Christophe Dooms,

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Jonas Yserbyt,

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Conny Gysemans,

Affiliation Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Ghislaine Gayan-Ramirez,

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Chantal Mathieu,

Affiliation Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Wim Janssens

* E-mail: wim.janssens@uzleuven.be

Affiliation Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯

1,25-Dihydroxyvitamin D Modulates Antibacterial and Inflammatory Response in Human Cigarette Smoke-Exposed Macrophages

Nele Heulens,
Hannelie Korf,
Carolien Mathyssen,
Stephanie Everaerts,
Elien De Smidt,
Christophe Dooms,
Jonas Yserbyt,
Conny Gysemans,
Ghislaine Gayan-Ramirez,
Chantal Mathieu

Published: August 11, 2016
https://doi.org/10.1371/journal.pone.0160482

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Alveolar macrophages
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Inflammation
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Antibacterials
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Phagocytosis
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Vitamin D
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Respiratory burst
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Macrophages
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Smoking habits
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