Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

Colin T. Shearn; David J. Orlicky; Rebecca L. McCullough; Hua Jiang; Kenneth N. Maclean; Kelly E. Mercer; Bangyan L. Stiles; Laura M. Saba; Martin J. Ronis; Dennis R. Petersen

doi:10.1371/journal.pone.0154152

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Open Access

Peer-reviewed

Research Article

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

Colin T. Shearn ,

* E-mail: Dennis.Petersen@ucdenver.edu (DRP); Colin.Shearn@ucdenver.edu (CTS)

Affiliation Skaggs School of Pharmaceutical Sciences and Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

http://orcid.org/0000-0002-9618-9885

⨯
David J. Orlicky,

Affiliation Department of Pathology, School of Medicine University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Rebecca L. McCullough,

Affiliation Skaggs School of Pharmaceutical Sciences and Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Hua Jiang,

Affiliation Department of Pediatrics, School of Medicine University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Kenneth N. Maclean,

Affiliation Department of Pediatrics, School of Medicine University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Kelly E. Mercer,

Affiliation Arkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AK, United States of America
⨯
Bangyan L. Stiles,

Affiliation Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, United States of America
⨯
Laura M. Saba,

Affiliation Skaggs School of Pharmaceutical Sciences and Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Martin J. Ronis,

Affiliation Arkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AK, United States of America
⨯
Dennis R. Petersen

* E-mail: Dennis.Petersen@ucdenver.edu (DRP); Colin.Shearn@ucdenver.edu (CTS)

Affiliation Skaggs School of Pharmaceutical Sciences and Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

Colin T. Shearn,
David J. Orlicky,
Rebecca L. McCullough,
Hua Jiang,
Kenneth N. Maclean,
Kelly E. Mercer,
Bangyan L. Stiles,
Laura M. Saba,
Martin J. Ronis,
Dennis R. Petersen

Published: April 28, 2016
https://doi.org/10.1371/journal.pone.0154152

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