Prevention Effects and Possible Molecular Mechanism of Mulberry Leaf Extract and its Formulation on Rats with Insulin-Insensitivity

Yan Liu; Xuemei Li; Chen Xie; Xiuzhen Luo; Yonggang Bao; Bin Wu; Yuchi Hu; Zhong Zhong; Chang Liu; MinJie Li

doi:10.1371/journal.pone.0152728

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Open Access

Peer-reviewed

Research Article

Prevention Effects and Possible Molecular Mechanism of Mulberry Leaf Extract and its Formulation on Rats with Insulin-Insensitivity

Yan Liu ,

Contributed equally to this work with: Yan Liu, Xuemei Li

Affiliation Research and Development Center of Amway (China), Shanghai, China
⨯
Xuemei Li ,

Contributed equally to this work with: Yan Liu, Xuemei Li

Affiliation Beijing Institute for Drug Control (Beijing Center For Health Food And Cosmetics Control), Beijing, China
⨯
Chen Xie,

Affiliation Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, 151 Malianwa North Road, Haidian District, Beijing 100193, China
⨯
Xiuzhen Luo,

Affiliation Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, 151 Malianwa North Road, Haidian District, Beijing 100193, China
⨯
Yonggang Bao,

Affiliation Beijing Pepnoch Co., Ltd, Beijing, China
⨯
Bin Wu,

Affiliation Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, 151 Malianwa North Road, Haidian District, Beijing 100193, China
⨯
Yuchi Hu,

Affiliation Beijing Institute for Drug Control (Beijing Center For Health Food And Cosmetics Control), Beijing, China
⨯
Zhong Zhong,

Affiliation Botanic Century (Beijing) Co., Ltd, Beijing, China
⨯
Chang Liu ,

* E-mail: cliu@implad.ac.cn (CL); Liz.Li@amway.com (MJL)

Affiliation Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, 151 Malianwa North Road, Haidian District, Beijing 100193, China
⨯
MinJie Li

* E-mail: cliu@implad.ac.cn (CL); Liz.Li@amway.com (MJL)

Affiliation Research and Development Center of Amway (China), Shanghai, China
⨯

Prevention Effects and Possible Molecular Mechanism of Mulberry Leaf Extract and its Formulation on Rats with Insulin-Insensitivity

Yan Liu,
Xuemei Li,
Chen Xie,
Xiuzhen Luo,
Yonggang Bao,
Bin Wu,
Yuchi Hu,
Zhong Zhong,
Chang Liu,
MinJie Li

Published: April 7, 2016
https://doi.org/10.1371/journal.pone.0152728

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