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Open Access
Peer-reviewed
Research Article
Implementation of a Pan-Genomic Approach to Investigate Holobiont-Infecting Microbe Interaction: A Case Report of a Leukemic Patient with Invasive Mucormycosis
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Samuel A. Shelburne,
Affiliations Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Nadim J. Ajami ,
Contributed equally to this work with: Nadim J. Ajami, Marcus C. Chibucos
Affiliation The Alkek Center for Metagenomics and Microbiome Research and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
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Marcus C. Chibucos ,
Contributed equally to this work with: Nadim J. Ajami, Marcus C. Chibucos
Affiliation Department of Microbiology & Immunology and Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Hannah C. Beird,
Affiliation Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Jeffrey Tarrand,
Affiliation Department of Laboratory Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Jessica Galloway-Peña,
Affiliation Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Nathan Albert,
Affiliation Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Roy F. Chemaly,
Affiliation Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Shashank S. Ghantoji,
Affiliation Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Lisa Marsh,
Affiliation Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Naveen Pemmaraju,
Affiliation Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Michael Andreeff,
Affiliation Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Elizabeth J. Shpall,
Affiliation Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Jennifer A. Wargo,
Affiliations Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Katayoun Rezvani,
Affiliation Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Amin Alousi,
Affiliation Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Vincent M. Bruno,
Affiliation The Alkek Center for Metagenomics and Microbiome Research and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
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Phillip A. Futreal,
Affiliation Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Joseph F. Petrosino,
Affiliation The Alkek Center for Metagenomics and Microbiome Research and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
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Dimitrios P. Kontoyiannis
* E-mail: dkontoyi@mdanderson.org
Affiliation Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Implementation of a Pan-Genomic Approach to Investigate Holobiont-Infecting Microbe Interaction: A Case Report of a Leukemic Patient with Invasive Mucormycosis
- Samuel A. Shelburne,
- Nadim J. Ajami,
- Marcus C. Chibucos,
- Hannah C. Beird,
- Jeffrey Tarrand,
- Jessica Galloway-Peña,
- Nathan Albert,
- Roy F. Chemaly,
- Shashank S. Ghantoji,
- Lisa Marsh
- Published: November 10, 2015
- https://doi.org/10.1371/journal.pone.0139851