Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

Paulina Kasperkiewicz; Marcin Poreba; Scott J. Snipas; S. Jack Lin; Daniel Kirchhofer; Guy S. Salvesen; Marcin Drag

doi:10.1371/journal.pone.0132818

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Peer-reviewed

Research Article

Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

Paulina Kasperkiewicz,

Affiliations Division of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wyb. Wyspianskiego 27, Wroclaw 50–370, Poland, Program in Cell Death and Survival Networks, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92024, United States of America
⨯
Marcin Poreba,

Affiliation Division of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wyb. Wyspianskiego 27, Wroclaw 50–370, Poland
⨯
Scott J. Snipas,

Affiliation Program in Cell Death and Survival Networks, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92024, United States of America
⨯
S. Jack Lin,

Affiliation Dept. of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States of America
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Daniel Kirchhofer,

Affiliation Dept. of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States of America
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Guy S. Salvesen ,

* E-mail: marcin.drag@pwr.edu.pl (MD); gsalvesen@sanfordburnham.org (GS)

Affiliation Program in Cell Death and Survival Networks, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92024, United States of America
⨯
Marcin Drag

* E-mail: marcin.drag@pwr.edu.pl (MD); gsalvesen@sanfordburnham.org (GS)

Affiliation Division of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wyb. Wyspianskiego 27, Wroclaw 50–370, Poland
⨯

Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

Paulina Kasperkiewicz,
Marcin Poreba,
Scott J. Snipas,
S. Jack Lin,
Daniel Kirchhofer,
Guy S. Salvesen,
Marcin Drag

Published: July 14, 2015
https://doi.org/10.1371/journal.pone.0132818

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