CD8+ T Cells Specific to Apoptosis-Associated Antigens Predict the Response to Tumor Necrosis Factor Inhibitor Therapy in Rheumatoid Arthritis

Alessandra Citro; Rossana Scrivo; Helene Martini; Carmela Martire; Paolo De Marzio; Anna Rita Vestri; John Sidney; Alessandro Sette; Vincenzo Barnaba; Guido Valesini

doi:10.1371/journal.pone.0128607

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Peer-reviewed

Research Article

CD8⁺ T Cells Specific to Apoptosis-Associated Antigens Predict the Response to Tumor Necrosis Factor Inhibitor Therapy in Rheumatoid Arthritis

Alessandra Citro,

Affiliation Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy
⨯
Rossana Scrivo,

Affiliation Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy
⨯
Helene Martini,

Affiliation Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy
⨯
Carmela Martire,

Affiliation Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy
⨯
Paolo De Marzio,

Affiliation Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy
⨯
Anna Rita Vestri,

Affiliation Dipartimento di Sanità Pubblica e Malattie Infettive, Sapienza Università di Roma, Rome, Italy
⨯
John Sidney,

Affiliation La Jolla Institute for Allergy and Immunology, San Diego, California 92121, United States of America
⨯
Alessandro Sette,

Affiliation La Jolla Institute for Allergy and Immunology, San Diego, California 92121, United States of America
⨯
Vincenzo Barnaba ,

* E-mail: vincenzo.barnaba@uniroma1.it

Affiliations Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy, Istituto Pasteur-Fondazione Cenci Bolognetti, 00185 Rome, Italy
⨯
Guido Valesini

Affiliation Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy
⨯

CD8⁺ T Cells Specific to Apoptosis-Associated Antigens Predict the Response to Tumor Necrosis Factor Inhibitor Therapy in Rheumatoid Arthritis

Alessandra Citro,
Rossana Scrivo,
Helene Martini,
Carmela Martire,
Paolo De Marzio,
Anna Rita Vestri,
John Sidney,
Alessandro Sette,
Vincenzo Barnaba,
Guido Valesini

Published: June 10, 2015
https://doi.org/10.1371/journal.pone.0128607

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T cells
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Apoptosis
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Enzyme-linked immunoassays
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Rheumatoid arthritis
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