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Open Access
Peer-reviewed
Research Article
Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis
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Dragana Božić,
Current address: Institute for Biological Research "Siniša Stanković", University of Belgrade, Serbia
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Dimitra Papaefthimiou,
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Kathleen Brückner,
Affiliation Leibniz Institute of Plant Biochemistry, Department of Cell and Metabolic Biology, Halle (Saale), Germany
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Ric C. H. de Vos,
Affiliations Plant Research International, Wageningen University and Research Centre, The Netherlands, Netherlands Metabolomics Centre, Leiden, The Netherlands
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Constantinos A. Tsoleridis,
Affiliation Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Dimitra Katsarou,
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Antigoni Papanikolaou,
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Irini Pateraki,
Current address: Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, 1871 Copenhagen, Denmark
Affiliation Department of Molecular Genetics, Centre for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Bellaterra-Cerdanyola del Vallés, 08193 Barcelona, Spain
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Fani M. Chatzopoulou,
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Eleni Dimitriadou,
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Stefanos Kostas,
Affiliation Laboratory of Floriculture, School of Agriculture, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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David Manzano,
Affiliation Department of Molecular Genetics, Centre for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Bellaterra-Cerdanyola del Vallés, 08193 Barcelona, Spain
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Ulschan Scheler,
Affiliation Leibniz Institute of Plant Biochemistry, Department of Cell and Metabolic Biology, Halle (Saale), Germany
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Albert Ferrer,
Affiliations Department of Molecular Genetics, Centre for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Bellaterra-Cerdanyola del Vallés, 08193 Barcelona, Spain, Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain
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Alain Tissier,
Affiliation Leibniz Institute of Plant Biochemistry, Department of Cell and Metabolic Biology, Halle (Saale), Germany
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Antonios M. Makris,
Affiliation Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thermi Thessaloniki, Greece
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Sotirios C. Kampranis,
Affiliation Department of Biochemistry, School of Medicine, University of Crete, P.O. Box 2208, 710 03 Heraklion, Greece
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Angelos K. Kanellis
* E-mail: kanellis@pharm.auth.gr
Affiliation Group of Biotechnology of Pharmaceutical Plants, Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
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Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis
- Dragana Božić,
- Dimitra Papaefthimiou,
- Kathleen Brückner,
- Ric C. H. de Vos,
- Constantinos A. Tsoleridis,
- Dimitra Katsarou,
- Antigoni Papanikolaou,
- Irini Pateraki,
- Fani M. Chatzopoulou,
- Eleni Dimitriadou
- Published: May 28, 2015
- https://doi.org/10.1371/journal.pone.0124106