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Open Access
Peer-reviewed
Research Article
Markers of Bone Metabolism Are Affected by Renal Function and Growth Hormone Therapy in Children with Chronic Kidney Disease
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Anke Doyon ,
* E-mail: anke.doyon@med.uni-heidelberg.de
Affiliation Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
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Dagmar-Christiane Fischer,
Affiliation Department of Pediatrics, University Hospital Rostock, Rostock, Germany
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Aysun Karabay Bayazit,
Affiliation Division of Pediatric Nephrology, Cukurova University, School of Medicine, Adana, Turkey
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Nur Canpolat,
Affiliation Division of Pediatric Nephrology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey
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Ali Duzova,
Affiliation Division of Pediatric Nephrology, Dpt. of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey
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Betül Sözeri,
Affiliation Division of Pediatric Nephrology, Ege University Medical Faculty, Izmir, Turkey
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Justine Bacchetta,
Affiliation Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France
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Ayse Balat,
Affiliation Department of Pediatric Nephrology, University of Gaziantep, Gaziantep, Turkey
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Anja Büscher,
Affiliation Division of Pediatric Nephrology, University Children’s Hospital, Essen, Germany
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Cengiz Candan,
Affiliation Division of Pediatric Nephrology, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey
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Nilgun Cakar,
Affiliation Diskapi Children’s Hospital, Ankara, Turkey
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Osman Donmez,
Affiliation Division of Pediatric Nephrology, Uludag University Faculty of Medicine, Bursa, Turkey
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Jiri Dusek,
Affiliation Pediatric Hospital, University Hospital Motol, Prague, Czech Republic
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Martina Heckel,
Affiliation University Children’s Hospital, Hamburg, Germany
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Günter Klaus,
Affiliation KfH Kidney Center for Children, Marburg, Germany
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Sevgi Mir,
Affiliation Division of Pediatric Nephrology, Ege University Medical Faculty, Izmir, Turkey
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Gül Özcelik,
Affiliation Department of Pediatric Nephrology, Sisli Educational and Research Hospital, Istanbul, Turkey
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Lale Sever,
Affiliation Division of Pediatric Nephrology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey
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Rukshana Shroff,
Affiliation Division of Pediatric Nephrology, Great Ormond Street Hospital, London, United Kingdom
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Enrico Vidal,
Affiliation Dialysis and Transplantation Department of Pediatrics, Padova, Italy
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Elke Wühl,
Affiliation Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
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Matthias Gondan,
Affiliation Department of Psychology, University of Copenhagen, Copenhagen, Denmark
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Anette Melk,
Affiliations Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany, Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Hannover, Germany
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Uwe Querfeld,
Affiliation Clinic of Pediatric Nephrology, Charite Children’s Hospital, Berlin, Germany
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Dieter Haffner ,
¶‡ These authors contributed equally to this work.
Affiliation Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
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Franz Schaefer ,
¶‡ These authors contributed equally to this work.
Affiliation Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
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for the 4C Study Consortium
¶Membership of the 4C Study Consortium is listed in the Acknowledgments.
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Markers of Bone Metabolism Are Affected by Renal Function and Growth Hormone Therapy in Children with Chronic Kidney Disease
- Anke Doyon,
- Dagmar-Christiane Fischer,
- Aysun Karabay Bayazit,
- Nur Canpolat,
- Ali Duzova,
- Betül Sözeri,
- Justine Bacchetta,
- Ayse Balat,
- Anja Büscher,
- Cengiz Candan

- Published: February 6, 2015
- https://doi.org/10.1371/journal.pone.0113482