Scorpion Venom Heat-Resistant Peptide (SVHRP) Enhances Neurogenesis and Neurite Outgrowth of Immature Neurons in Adult Mice by Up-Regulating Brain-Derived Neurotrophic Factor (BDNF)

Tao Wang; Shi-Wei Wang; Yue Zhang; Xue-Fei Wu; Yan Peng; Zhen Cao; Bi-Ying Ge; Xi Wang; Qiong Wu; Jin-Tao Lin; Wan-Qin Zhang; Shao Li; Jie Zhao

doi:10.1371/journal.pone.0109977

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Peer-reviewed

Research Article

Scorpion Venom Heat-Resistant Peptide (SVHRP) Enhances Neurogenesis and Neurite Outgrowth of Immature Neurons in Adult Mice by Up-Regulating Brain-Derived Neurotrophic Factor (BDNF)

Tao Wang ,

Contributed equally to this work with: Tao Wang, Shi-Wei Wang

Affiliations Department of Physiology, Dalian Medical University, Dalian, China, Liaoning Engineering Technology Centre of Target-based Nature Products for Prevention and Treatment of Ageing-related Neurodegeneration, Dalian, China
⨯
Shi-Wei Wang ,

Contributed equally to this work with: Tao Wang, Shi-Wei Wang

Affiliations Department of Physiology, Dalian Medical University, Dalian, China, The Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia
⨯
Yue Zhang,

Affiliation Liaoning Engineering Technology Centre of Target-based Nature Products for Prevention and Treatment of Ageing-related Neurodegeneration, Dalian, China
⨯
Xue-Fei Wu,

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Yan Peng,

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Zhen Cao,

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Bi-Ying Ge,

Affiliation Liaoning Engineering Technology Centre of Target-based Nature Products for Prevention and Treatment of Ageing-related Neurodegeneration, Dalian, China
⨯
Xi Wang,

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Qiong Wu,

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Jin-Tao Lin,

Affiliation Department of Biotechnology, Dalian Medical University, Dalian, China
⨯
Wan-Qin Zhang,

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Shao Li ,

* E-mail: dlzhaoj@163.com (JZ); lishao89@hotmail.com (SL)

Affiliation Department of Physiology, Dalian Medical University, Dalian, China
⨯
Jie Zhao

* E-mail: dlzhaoj@163.com (JZ); lishao89@hotmail.com (SL)

Affiliations Department of Physiology, Dalian Medical University, Dalian, China, Liaoning Engineering Technology Centre of Target-based Nature Products for Prevention and Treatment of Ageing-related Neurodegeneration, Dalian, China
⨯

Scorpion Venom Heat-Resistant Peptide (SVHRP) Enhances Neurogenesis and Neurite Outgrowth of Immature Neurons in Adult Mice by Up-Regulating Brain-Derived Neurotrophic Factor (BDNF)

Tao Wang,
Shi-Wei Wang,
Yue Zhang,
Xue-Fei Wu,
Yan Peng,
Zhen Cao,
Bi-Ying Ge,
Xi Wang,
Qiong Wu,
Jin-Tao Lin

Published: October 9, 2014
https://doi.org/10.1371/journal.pone.0109977

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Astrocytes
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