Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis

• Milos Lazic ,

  Contributed equally to this work with: Milos Lazic, Maria Eugenia Inzaugarat

  Affiliation Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• Maria Eugenia Inzaugarat ,

  Contributed equally to this work with: Milos Lazic, Maria Eugenia Inzaugarat

  Affiliation Institute of Immunology, Genetics and Metabolism, CONICET-UBA, Buenos Aires, Argentina

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• Davide Povero,

  Affiliation Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• Iris C. Zhao,

  Affiliation Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

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• Mark Chen,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Madlena Nalbandian,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Yury I. Miller,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Alejandra C. Cherñavsky,

  Affiliation Institute of Immunology, Genetics and Metabolism, CONICET-UBA, Buenos Aires, Argentina

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• Ariel E. Feldstein,

  Affiliation Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• Dorothy D. Sears

  * E-mail: dsears@ucsd.edu

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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