Aging and CaMKII Alter Intracellular Ca2+ Transients and Heart Rhythm in Drosophila melanogaster

Manuela Santalla; Carlos A. Valverde; Ezequiel Harnichar; Ezequiel Lacunza; Javier Aguilar-Fuentes; Alicia Mattiazzi; Paola Ferrero

doi:10.1371/journal.pone.0101871

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Peer-reviewed

Research Article

Aging and CaMKII Alter Intracellular Ca²⁺ Transients and Heart Rhythm in Drosophila melanogaster

Manuela Santalla,

Affiliations Centro de Investigaciones Cardiovasculares, CONICET-La Plata, Facultad de Medicina, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina, Departamento de Ciencias Básicas y Experimentales, Universidad Nacional del Noroeste de Buenos Aires, Pergamino, Buenos Aires, Argentina
⨯
Carlos A. Valverde,

Affiliation Centro de Investigaciones Cardiovasculares, CONICET-La Plata, Facultad de Medicina, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina
⨯
Ezequiel Harnichar,

Affiliation Centro de Investigaciones Cardiovasculares, CONICET-La Plata, Facultad de Medicina, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina
⨯
Ezequiel Lacunza,

Affiliation Centro de Investigaciones Inmunológicas Básicas y Aplicadas, CONICET-La Plata, Facultad de Medicina, Universidad Nacional de La Plata La Plata, Buenos Aires, Argentina
⨯
Javier Aguilar-Fuentes,

Affiliation Universidad Autónoma de Chiapas, Centro Mesoamericano de Estudios en Salud Pública y Desastres, Nodo Tapachula, Laboratorio de Epigenética del Neurodesarrollo y Neurobiología Molecular, Tapachula, Chiapas, México
⨯
Alicia Mattiazzi,

Affiliation Centro de Investigaciones Cardiovasculares, CONICET-La Plata, Facultad de Medicina, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina
⨯
Paola Ferrero

* E-mail: pferrero@unnoba.edu.ar

Affiliations Centro de Investigaciones Cardiovasculares, CONICET-La Plata, Facultad de Medicina, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina, Departamento de Ciencias Básicas y Experimentales, Universidad Nacional del Noroeste de Buenos Aires, Pergamino, Buenos Aires, Argentina
⨯

Aging and CaMKII Alter Intracellular Ca²⁺ Transients and Heart Rhythm in Drosophila melanogaster

Manuela Santalla,
Carlos A. Valverde,
Ezequiel Harnichar,
Ezequiel Lacunza,
Javier Aguilar-Fuentes,
Alicia Mattiazzi,
Paola Ferrero

Published: July 8, 2014
https://doi.org/10.1371/journal.pone.0101871

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Heart
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Drosophila
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Heart rate
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