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Intracytoplasmic Sperm Injection Using DNA-Fragmented Sperm in Mice Negatively Affects Embryo-Derived Embryonic Stem Cells, Reduces the Fertility of Male Offspring and Induces Heritable Changes in Epialleles
- Priscila Ramos-Ibeas,
- Alexandra Calle,
- Raúl Fernández-González,
- Ricardo Laguna-Barraza,
- Eva Pericuesta,
- Antonia Calero,
- Miguel Ángel Ramírez,
- Alfonso Gutiérrez-Adán
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- Published: April 17, 2014
- https://doi.org/10.1371/journal.pone.0095625