Functionally Significant, Rare Transcription Factor Variants in Tetralogy of Fallot

Ana Töpf; Helen R. Griffin; Elise Glen; Rachel Soemedi; Danielle L. Brown; Darroch Hall; Thahira J. Rahman; Jyrki J. Eloranta; Christoph Jüngst; A. Graham Stuart; John O'Sullivan; Bernard D. Keavney; Judith A. Goodship

doi:10.1371/journal.pone.0095453

Loading metrics

Open Access

Peer-reviewed

Research Article

Functionally Significant, Rare Transcription Factor Variants in Tetralogy of Fallot

Ana Töpf,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Helen R. Griffin,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Elise Glen,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Rachel Soemedi,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Danielle L. Brown,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Darroch Hall,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Thahira J. Rahman,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Jyrki J. Eloranta,

Affiliation Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Zurich, Switzerland
⨯
Christoph Jüngst,

Affiliations Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Zurich, Switzerland, Department of Medicine II, Saarland University Medical Center, Homburg, Germany
⨯
A. Graham Stuart,

Affiliation Bristol Royal Hospital for Children, Bristol, United Kingdom
⨯
John O'Sullivan,

Affiliation Paediatric Cardiology, Freeman Hospital Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom
⨯
Bernard D. Keavney ,

* E-mail: judith.goodship@ncl.ac.uk (BDK); bernard.keavney@manchester.ac.uk (JAG)

Affiliations Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, Institute of Cardiovascular Sciences, The University of Manchester, Manchester, United Kingdom
⨯
Judith A. Goodship

* E-mail: judith.goodship@ncl.ac.uk (BDK); bernard.keavney@manchester.ac.uk (JAG)

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯

Functionally Significant, Rare Transcription Factor Variants in Tetralogy of Fallot

Ana Töpf,
Helen R. Griffin,
Elise Glen,
Rachel Soemedi,
Danielle L. Brown,
Darroch Hall,
Thahira J. Rahman,
Jyrki J. Eloranta,
Christoph Jüngst,
A. Graham Stuart

Published: August 5, 2014
https://doi.org/10.1371/journal.pone.0095453

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Alanine
Is the Subject Area "Alanine" applicable to this article?

Thanks for your feedback.
3' UTR
Is the Subject Area "3' UTR" applicable to this article?

Thanks for your feedback.
Pulmonary arteries
Is the Subject Area "Pulmonary arteries" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Genetic networks
Is the Subject Area "Genetic networks" applicable to this article?

Thanks for your feedback.
Transactivation
Is the Subject Area "Transactivation" applicable to this article?

Thanks for your feedback.