Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice

Lukas E. Dow; Zeina Nasr; Michael Saborowski; Saya H. Ebbesen; Eusebio Manchado; Nilgun Tasdemir; Teresa Lee; Jerry Pelletier; Scott W. Lowe

doi:10.1371/journal.pone.0095236

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Peer-reviewed

Research Article

Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice

Lukas E. Dow,

Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Zeina Nasr,

Affiliation Department of Biochemistry, McGill University, Montreal, Quebec, Canada
⨯
Michael Saborowski,

Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Saya H. Ebbesen,

Affiliations Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Eusebio Manchado,

Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Nilgun Tasdemir,

Affiliations Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Teresa Lee,

Affiliation Department of Biochemistry, McGill University, Montreal, Quebec, Canada
⨯
Jerry Pelletier ,

* E-mail: jerry.pelletier@mcgill.ca (JP); lowes@mskcc.org (SWL)

Affiliations Department of Biochemistry, McGill University, Montreal, Quebec, Canada, The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec, Canada
⨯
Scott W. Lowe

* E-mail: jerry.pelletier@mcgill.ca (JP); lowes@mskcc.org (SWL)

Affiliations Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯

Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice

Lukas E. Dow,
Zeina Nasr,
Michael Saborowski,
Saya H. Ebbesen,
Eusebio Manchado,
Nilgun Tasdemir,
Teresa Lee,
Jerry Pelletier,
Scott W. Lowe

Published: April 17, 2014
https://doi.org/10.1371/journal.pone.0095236

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