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Open Access
Peer-reviewed
Research Article
Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions
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Jens Durruthy-Durruthy,
Affiliation Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology and Department of Genetics, Stanford University, Stanford, California, United States of America
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Sharon F. Briggs,
Affiliation Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology and Department of Genetics, Stanford University, Stanford, California, United States of America
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Jason Awe,
Affiliations Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research, University of California Los Angeles, Los Angeles, California, United States of America, Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
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Cyril Y. Ramathal,
Affiliation Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology and Department of Genetics, Stanford University, Stanford, California, United States of America
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Saravanan Karumbayaram,
Affiliations Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research, University of California Los Angeles, Los Angeles, California, United States of America, Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, California, United States of America
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Patrick C. Lee,
Affiliations Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research, University of California Los Angeles, Los Angeles, California, United States of America, Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
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Julia D. Heidmann,
Affiliation Veterans Affairs Palo Alto Health Care System, Stanford University, Palo Alto, California, United States of America
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Amander Clark,
Affiliations Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research, University of California Los Angeles, Los Angeles, California, United States of America, Department of Molecular, Cellular, and Developmental Biology, Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America
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Ioannis Karakikes,
Affiliations Stanford Cardiovascular Institute, Stanford University, Stanford, California, United States of America, Department of Cardiology, Department of Medicine, Stanford University, Stanford, California, United States of America
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Kyle M. Loh,
Affiliation Department of Developmental Biology, Stanford University, Stanford, California, United States of America
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Joseph C. Wu,
Affiliations Stanford Cardiovascular Institute, Stanford University, Stanford, California, United States of America, Department of Cardiology, Department of Medicine, Stanford University, Stanford, California, United States of America
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Andrew R. Hoffman,
Affiliation Veterans Affairs Palo Alto Health Care System, Stanford University, Palo Alto, California, United States of America
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James Byrne,
Affiliations Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research, University of California Los Angeles, Los Angeles, California, United States of America, Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
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Renee A. Reijo Pera,
Affiliation Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology and Department of Genetics, Stanford University, Stanford, California, United States of America
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Vittorio Sebastiano
* E-mail: vsebast@stanford.edu
Affiliation Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology and Department of Genetics, Stanford University, Stanford, California, United States of America
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Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions
- Jens Durruthy-Durruthy,
- Sharon F. Briggs,
- Jason Awe,
- Cyril Y. Ramathal,
- Saravanan Karumbayaram,
- Patrick C. Lee,
- Julia D. Heidmann,
- Amander Clark,
- Ioannis Karakikes,
- Kyle M. Loh
- Published: April 9, 2014
- https://doi.org/10.1371/journal.pone.0094231