Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (IM), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011)

Mary E. Enama; Julie E. Ledgerwood; Laura Novik; Martha C. Nason; Ingelise J. Gordon; LaSonji Holman; Robert T. Bailer; Mario Roederer; Richard A. Koup; John R. Mascola; Gary J. Nabel; Barney S. Graham; the VRC 011 Study Team

doi:10.1371/journal.pone.0091366

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Open Access

Peer-reviewed

Research Article

Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (IM), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011)

Mary E. Enama,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Julie E. Ledgerwood,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Laura Novik,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Martha C. Nason,

Affiliation Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Ingelise J. Gordon,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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LaSonji Holman,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Robert T. Bailer,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Mario Roederer,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Richard A. Koup,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
John R. Mascola,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Gary J. Nabel,

Current address: Sanofi-Pasteur, Cambridge, Massachusetts, United States of America

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Barney S. Graham ,

* E-mail: bgraham@nih.gov

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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the VRC 011 Study Team

¶Membership of the VRC 011 Study Team is provided in the Acknowledgments.
⨯

Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (IM), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011)

Mary E. Enama,
Julie E. Ledgerwood,
Laura Novik,
Martha C. Nason,
Ingelise J. Gordon,
LaSonji Holman,
Robert T. Bailer,
Mario Roederer,
Richard A. Koup,
John R. Mascola

Published: March 12, 2014
https://doi.org/10.1371/journal.pone.0091366

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