Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering

Open Access

Peer-reviewed

Research Article

Jia Liu,

Affiliation The Departments of Chemistry and Cell and Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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Thomas Gaj,

Affiliation The Departments of Chemistry and Cell and Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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James T. Patterson,

Affiliation The Departments of Chemistry and Cell and Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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Shannon J. Sirk,

Affiliation The Departments of Chemistry and Cell and Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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Carlos F. Barbas III

* E-mail: carlos@scripps.edu

Affiliation The Departments of Chemistry and Cell and Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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TALENs
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Protease inhibitor therapy
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Gene knockout
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Nucleases
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HeLa cells
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Gene disruption
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Zinc finger nucleases
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Gene delivery
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