An Association Study between Hypoxia Inducible Factor-1alpha (HIF-1α) Polymorphisms and Osteonecrosis

Georgia Chachami; Alkmini Kalousi; Loukia Papatheodorou; Aggeliki Lyberopoulou; Vasileios Nasikas; Keiji Tanimoto; George Simos; Konstantinos N. Malizos; Eleni Georgatsou

doi:10.1371/journal.pone.0079647

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Peer-reviewed

Research Article

An Association Study between Hypoxia Inducible Factor-1alpha (HIF-1α) Polymorphisms and Osteonecrosis

Georgia Chachami,

Affiliations Laboratory of Biochemistry, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece, Institute of Biomedical Research and Technology (BIOMED/CERETETH), Larissa, Greece
⨯
Alkmini Kalousi,

Affiliations Laboratory of Biochemistry, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece, Institute of Biomedical Research and Technology (BIOMED/CERETETH), Larissa, Greece
⨯
Loukia Papatheodorou,

Affiliation Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece
⨯
Aggeliki Lyberopoulou,

Affiliations Laboratory of Biochemistry, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece, Institute of Biomedical Research and Technology (BIOMED/CERETETH), Larissa, Greece
⨯
Vasileios Nasikas,

Affiliation Laboratory of Biochemistry, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece
⨯
Keiji Tanimoto,

Affiliation Department of Translational Cancer Research, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
⨯
George Simos,

Affiliations Laboratory of Biochemistry, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece, Institute of Biomedical Research and Technology (BIOMED/CERETETH), Larissa, Greece
⨯
Konstantinos N. Malizos,

Affiliations Institute of Biomedical Research and Technology (BIOMED/CERETETH), Larissa, Greece, Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece
⨯
Eleni Georgatsou

* E-mail: egeorgat@med.uth.gr

Affiliations Laboratory of Biochemistry, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece, Institute of Biomedical Research and Technology (BIOMED/CERETETH), Larissa, Greece
⨯

An Association Study between Hypoxia Inducible Factor-1alpha (HIF-1α) Polymorphisms and Osteonecrosis

Georgia Chachami,
Alkmini Kalousi,
Loukia Papatheodorou,
Aggeliki Lyberopoulou,
Vasileios Nasikas,
Keiji Tanimoto,
George Simos,
Konstantinos N. Malizos,
Eleni Georgatsou

Published: November 18, 2013
https://doi.org/10.1371/journal.pone.0079647

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Variant genotypes
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Single nucleotide polymorphisms
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Etiology
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Hypoxia
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Protein expression
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Oxygen
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