Functional Analysis of a Breast Cancer-Associated FGFR2 Single Nucleotide Polymorphism Using Zinc Finger Mediated Genome Editing

Open Access

Peer-reviewed

Research Article

Luisa J. Robbez-Masson,

Affiliation Centre for Tumour Biology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
⨯
Csaba Bödör,

Affiliation Centre for Haemato-Oncology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
⨯
J. Louise Jones,

Affiliation Centre for Tumour Biology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
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Helen C. Hurst,

Affiliation Centre for Tumour Biology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
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Jude Fitzgibbon,

Affiliation Centre for Haemato-Oncology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
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Ian R. Hart,

Affiliation Centre for Tumour Biology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
⨯
Richard P. Grose

* E-mail: r.p.grose@qmul.ac.uk

Affiliation Centre for Tumour Biology, Barts Cancer Institute – a Cancer Research UK Centre of Excellence, Queen Mary University of London, London, United Kingdom
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Breast cancer
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Cloning
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Single nucleotide polymorphisms
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Heterozygosity
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Zinc finger nucleases
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Cancer risk factors
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Alleles
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Fibroblast growth factor
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