Association between Serum Ferritin and Osteocalcin as a Potential Mechanism Explaining the Iron-Induced Insulin Resistance

Martí Juanola-Falgarona; José Cándido-Fernández; Jordi Salas-Salvadó; Miguel A. Martínez-González; Ramón Estruch; Miquel Fiol; Victoria Arija-Val; Mònica Bulló; for the PREDIMED Study Investigators

doi:10.1371/journal.pone.0076433

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Open Access

Peer-reviewed

Research Article

Association between Serum Ferritin and Osteocalcin as a Potential Mechanism Explaining the Iron-Induced Insulin Resistance

Martí Juanola-Falgarona,

Affiliations Human Nutrition Unit and Preventive Medicine Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, Reus, Spain, CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain
⨯
José Cándido-Fernández,

Affiliation Human Nutrition Unit and Preventive Medicine Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, Reus, Spain
⨯
Jordi Salas-Salvadó ,

* E-mail: monica.bullo@urv.cat (MB); jordi.salas@urv.cat (JS-S)

Affiliations Human Nutrition Unit and Preventive Medicine Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, Reus, Spain, CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain
⨯
Miguel A. Martínez-González,

Affiliations CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain, Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain
⨯
Ramón Estruch,

Affiliations CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain, Department of Internal Medicine, Institut d'Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain
⨯
Miquel Fiol,

Affiliations CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain, University Institute for Health Sciences Investigation, Palma de Mallorca, Spain
⨯
Victoria Arija-Val,

Affiliation Human Nutrition Unit and Preventive Medicine Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, Reus, Spain
⨯
Mònica Bulló ,

* E-mail: monica.bullo@urv.cat (MB); jordi.salas@urv.cat (JS-S)

Affiliations Human Nutrition Unit and Preventive Medicine Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, Reus, Spain, CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain
⨯
for the PREDIMED Study Investigators

Association between Serum Ferritin and Osteocalcin as a Potential Mechanism Explaining the Iron-Induced Insulin Resistance

Martí Juanola-Falgarona,
José Cándido-Fernández,
Jordi Salas-Salvadó,
Miguel A. Martínez-González,
Ramón Estruch,
Miquel Fiol,
Victoria Arija-Val,
Mònica Bulló,
for the PREDIMED Study Investigators

Published: October 22, 2013
https://doi.org/10.1371/journal.pone.0076433

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Osteocalcin
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Ferritin
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Glucose metabolism
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Adiponectin
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Insulin
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Insulin resistance
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Glucose
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Type 2 diabetes
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