A Comparison of Methods for Clustering 16S rRNA Sequences into OTUs

Open Access

Peer-reviewed

Research Article

Wei Chen,

Affiliations College of Automation, Northwestern Polytechnical University, Xi'an, Shaanxi, China, Department of Biostatistics, School of Public Health, Yale University, New Haven, Connecticut, United States of America
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Clarence K. Zhang,

Affiliation Keck Biotechnology Laboratory, Biostatistics Resource, School of Medicine, Yale University, New Haven, Connecticut, United States of America
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Yongmei Cheng,

Affiliation College of Automation, Northwestern Polytechnical University, Xi'an, Shaanxi, China
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Shaowu Zhang,

Affiliation College of Automation, Northwestern Polytechnical University, Xi'an, Shaanxi, China
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Hongyu Zhao

* E-mail: hongyu.zhao@yale.edu

Affiliations Department of Biostatistics, School of Public Health, Yale University, New Haven, Connecticut, United States of America, Keck Biotechnology Laboratory, Biostatistics Resource, School of Medicine, Yale University, New Haven, Connecticut, United States of America
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Algorithms
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Ribosomal RNA
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Crops
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Hierarchical clustering
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Clustering algorithms
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Microbial taxonomy
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Sequence alignment
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Taxonomy
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