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Open Access
Peer-reviewed
Research Article
Genetic Associations of Type 2 Diabetes with Islet Amyloid Polypeptide Processing and Degrading Pathways in Asian Populations
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Vincent Kwok Lim Lam,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Ronald Ching Wan Ma,
Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China, Li Ka Shing Institute of Health, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Heung Man Lee,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Cheng Hu,
Affiliation Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, People's Republic of China
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Kyong Soo Park,
Affiliation Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and Department of Internal Medicine, College of Medicine, Seoul National University, Chongno-gu, Seoul, Korea
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Hiroto Furuta,
Affiliation First Department of Medicine, Wakayama Medical University, Wakayama, Japan
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Ying Wang,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Claudia Ha Ting Tam,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Xueling Sim,
Affiliation Centre for Molecular Epidemiology, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
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Daniel Peng-Keat Ng,
Affiliation Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
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Jianjun Liu,
Affiliations Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore
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Tien-Yin Wong,
Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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E. Shyong Tai,
Affiliations Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore
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Andrew P. Morris,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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DIAGRAM Consortium ,
¶Membership of the DIAGRAM Consortium is provided in Text S2.
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Nelson Leung Sang Tang,
Affiliation Department of Chemical Pathology, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Jean Woo,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Ping Chung Leung,
Affiliation Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Alice Pik Shan Kong,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Risa Ozaki,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Wei Ping Jia,
Affiliation Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, People's Republic of China
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Hong Kyu Lee,
Current address: Department of Internal Medicine, Eulji University, Hangeulbiseok-gil, Hagye-dong, Nowon-gu, Seoul, Korea
Affiliation Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and Department of Internal Medicine, College of Medicine, Seoul National University, Chongno-gu, Seoul, Korea
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Kishio Nanjo,
Affiliation First Department of Medicine, Wakayama Medical University, Wakayama, Japan
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Gang Xu,
Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China, Li Ka Shing Institute of Health, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Maggie Chor Yin Ng,
Current address: Center for Diabetes Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Wing-Yee So,
Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Juliana Chung Ngor Chan
* E-mail: jchan@cuhk.edu.hk
Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China, Li Ka Shing Institute of Health, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China
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Genetic Associations of Type 2 Diabetes with Islet Amyloid Polypeptide Processing and Degrading Pathways in Asian Populations
- Vincent Kwok Lim Lam,
- Ronald Ching Wan Ma,
- Heung Man Lee,
- Cheng Hu,
- Kyong Soo Park,
- Hiroto Furuta,
- Ying Wang,
- Claudia Ha Ting Tam,
- Xueling Sim,
- Daniel Peng-Keat Ng
- Published: June 11, 2013
- https://doi.org/10.1371/journal.pone.0062378