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Open Access
Peer-reviewed
Research Article
Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling
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Peter Reinhardt,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Michael Glatza,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Kathrin Hemmer,
Affiliation Stem Cell Biology and Regeneration Group, Institute of Cell Biology, Center for Molecular Biology of Inflammation, Westfälische Wilhelms-Universität Münster, Münster, North Rhine-Westphalia, Germany
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Yaroslav Tsytsyura,
Affiliation Westfälische Wilhelms-Universität Münster, Institute for Medical Physics and Biophysics, Cellular Biophysics Group, Münster, North Rhine-Westphalia, Germany
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Cora S. Thiel,
Affiliation Westfälische Wilhelms-Universität Münster, Institute for Medical Physics and Biophysics, Cellular Biophysics Group, Münster, North Rhine-Westphalia, Germany
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Susanne Höing,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Sören Moritz,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Juan A. Parga,
Affiliations Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany, Center for Research in Molecular Medicine and Chronic Diseases at the University of Santiago de Compostela, Santiago de Compostela, Spain
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Lydia Wagner,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Jan M. Bruder,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Guangming Wu,
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Benjamin Schmid,
Affiliation Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tübingen, and German Center for Neurodegenerative Diseases, Tübingen, Baden-Württemburg, Germany
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Albrecht Röpke,
Affiliation Institute for Human Genetics, University of Münster, Münster, North Rhine Westphalia, Germany
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Jürgen Klingauf,
Affiliation Westfälische Wilhelms-Universität Münster, Institute for Medical Physics and Biophysics, Cellular Biophysics Group, Münster, North Rhine-Westphalia, Germany
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Jens C. Schwamborn,
Affiliation Stem Cell Biology and Regeneration Group, Institute of Cell Biology, Center for Molecular Biology of Inflammation, Westfälische Wilhelms-Universität Münster, Münster, North Rhine-Westphalia, Germany
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Thomas Gasser,
Affiliation Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tübingen, and German Center for Neurodegenerative Diseases, Tübingen, Baden-Württemburg, Germany
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Hans R. Schöler ,
* E-mail: office@mpi-muenster.mpg.de (HRS); jsternec@mpi-muenster.mpg.de (JS)
Affiliations Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany, Medical Faculty, University of Münster, Münster, North Rhine-Westphalia, Germany
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Jared Sterneckert
* E-mail: office@mpi-muenster.mpg.de (HRS); jsternec@mpi-muenster.mpg.de (JS)
Affiliation Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine Westphalia, Germany
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Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling
- Peter Reinhardt,
- Michael Glatza,
- Kathrin Hemmer,
- Yaroslav Tsytsyura,
- Cora S. Thiel,
- Susanne Höing,
- Sören Moritz,
- Juan A. Parga,
- Lydia Wagner,
- Jan M. Bruder
- Published: March 22, 2013
- https://doi.org/10.1371/journal.pone.0059252