Aprotinin May Increase Mortality in Low and Intermediate Risk but Not in High Risk Cardiac Surgical Patients Compared to Tranexamic Acid and ε-Aminocaproic Acid – A Meta-Analysis of Randomised and Observational Trials of over 30.000 Patients

Open Access

Peer-reviewed

Research Article

Patrick Meybohm ,

* E-mail: patrick.meybohm@kgu.de

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Eva Herrmann,

Affiliation Institute of Biostatistics and Mathematical Modelling, University Hospital Frankfurt, Frankfurt am Main, Germany
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Julia Nierhoff,

Affiliation Institute of Biostatistics and Mathematical Modelling, University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Kai Zacharowski

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
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Medical risk factors
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Surgical and invasive medical procedures
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Cardiac surgery
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Lysine
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Hemorrhage
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Blood transfusion
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Metaanalysis
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