Improved Glycaemia Correlates with Liver Fat Reduction in Obese, Type 2 Diabetes, Patients Given Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists

Daniel J. Cuthbertson; Andrew Irwin; Chris J. Gardner; Christina Daousi; Tej Purewal; Niall Furlong; Niru Goenka; E. Louise Thomas; Valerie L. Adams; Sudeep P. Pushpakom; Munir Pirmohamed; Graham J. Kemp

doi:10.1371/journal.pone.0050117

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Open Access

Peer-reviewed

Research Article

Improved Glycaemia Correlates with Liver Fat Reduction in Obese, Type 2 Diabetes, Patients Given Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists

Daniel J. Cuthbertson ,

* E-mail: daniel.cuthbertson@liverpool.ac.uk

Affiliations Department of Obesity and Endocrinology, University Hospital Aintree, Liverpool, Liverpool, United Kingdom, Department of Obesity and Endocrinology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, Liverpool, United Kingdom
⨯
Andrew Irwin,

Affiliation Department of Obesity and Endocrinology, University Hospital Aintree, Liverpool, Liverpool, United Kingdom
⨯
Chris J. Gardner,

Affiliation Department of Obesity and Endocrinology, University Hospital Aintree, Liverpool, Liverpool, United Kingdom
⨯
Christina Daousi,

Affiliations Department of Obesity and Endocrinology, University Hospital Aintree, Liverpool, Liverpool, United Kingdom, Department of Obesity and Endocrinology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, Liverpool, United Kingdom
⨯
Tej Purewal,

Affiliation Department of Diabetes and Endocrinology, Royal Liverpool University Hospital, Liverpool, United Kingdom
⨯
Niall Furlong,

Affiliation Department of Diabetes and Endocrinology, St Helen’s and Knowsley, Whiston, Whiston, United Kingdom
⨯
Niru Goenka,

Affiliation Department of Diabetes and Endocrinology, Countess of Chester Hospital, Chester, United Kingdom
⨯
E. Louise Thomas,

Affiliation Metabolic and Molecular Imaging Group, MRC Clinical Sciences Centre, Imperial College London, London, United Kingdom
⨯
Valerie L. Adams,

Affiliation Magnetic Resonance and Image Analysis Research Centre, University of Liverpool, Liverpool, United Kingdom
⨯
Sudeep P. Pushpakom,

Affiliation The Wolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Munir Pirmohamed,

Affiliation The Wolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Graham J. Kemp

Affiliations Magnetic Resonance and Image Analysis Research Centre, University of Liverpool, Liverpool, United Kingdom, Department of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom
⨯

Improved Glycaemia Correlates with Liver Fat Reduction in Obese, Type 2 Diabetes, Patients Given Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists

Daniel J. Cuthbertson,
Andrew Irwin,
Chris J. Gardner,
Christina Daousi,
Tej Purewal,
Niall Furlong,
Niru Goenka,
E. Louise Thomas,
Valerie L. Adams,
Sudeep P. Pushpakom

Published: December 6, 2012
https://doi.org/10.1371/journal.pone.0050117

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Weight loss
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