Phosphorylation of C3a Receptor at Multiple Sites Mediates Desensitization, β-Arrestin-2 Recruitment and Inhibition of NF-κB Activity in Mast Cells

Open Access

Peer-reviewed

Research Article

Kshitij Gupta,

Affiliation Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Hariharan Subramanian,

Affiliation Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Andreas Klos,

Affiliation Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany
⨯
Hydar Ali

* E-mail: alih@upenn.edu

Affiliation Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Phosphorylation
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Mast cells
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Cell degranulation
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Luciferase
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Transfection
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Chemokines
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G protein coupled receptors
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