Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System

Weifeng Zhang; Yuanxu Guo; Chen Zhang; Haiyan Ji; Wenpeng Meng; Dongyang Wang; Xing Li; Qinwen Mao; Haibin Xia

doi:10.1371/journal.pone.0045169

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Open Access

Peer-reviewed

Research Article

Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System

Weifeng Zhang,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Yuanxu Guo,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Chen Zhang,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Haiyan Ji,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Wenpeng Meng,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Dongyang Wang,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Xing Li,

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯
Qinwen Mao ,

* E-mail: q-mao@northwestern.edu (QM); hbxia2001@163.com (HX)

Affiliation Departmet of Pathology, Northwestern University Feinberg School of Medicine Chicago, Chicago, Illinois, United States of America
⨯
Haibin Xia

* E-mail: q-mao@northwestern.edu (QM); hbxia2001@163.com (HX)

Affiliation Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi, People’s Republic of China
⨯

Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System

Weifeng Zhang,
Yuanxu Guo,
Chen Zhang,
Haiyan Ji,
Wenpeng Meng,
Dongyang Wang,
Xing Li,
Qinwen Mao,
Haibin Xia

Published: September 18, 2012
https://doi.org/10.1371/journal.pone.0045169

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Luciferase
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