Local Delivery of Nimodipine by Prolonged-Release Microparticles—Feasibility, Effectiveness and Dose-Finding in Experimental Subarachnoid Hemorrhage

• Daniel Hänggi ,

  * E-mail: daniel.haenggi@uni-duesseldorf.de

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Jason Perrin,

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Sven Eicker,

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Kerim Beseoglu,

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Nima Etminan,

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Marcel Alexander Kamp,

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Hi-Jae Heiroth,

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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• Nadia Bege,

  Affiliation Department of Pharmaceutics and Biopharmacy, Philipps-University, Marburg, Germany

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• Stephan Macht,

  Affiliation Institute of Neuroradiology, Heinrich-Heine-University, Düsseldorf, Germany

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• Katrin Frauenknecht,

  Affiliation Department of Neuropathology, University Medical Center of the Johannes-Gutenberg-University, Mainz, Germany

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• Clemens Sommer,

  Affiliation Department of Neuropathology, University Medical Center of the Johannes-Gutenberg-University, Mainz, Germany

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• Thomas Kissel,

  Affiliation Department of Pharmaceutics and Biopharmacy, Philipps-University, Marburg, Germany

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• Hans-Jakob Steiger

  Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

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