Calcium Channel Blockers, More than Diuretics, Enhance Vascular Protective Effects of Angiotensin Receptor Blockers in Salt-Loaded Hypertensive Rats

Eiichiro Yamamoto; Keiichiro Kataoka; Yi-Fei Dong; Nobutaka Koibuchi; Kensuke Toyama; Daisuke Sueta; Tetsuji Katayama; Osamu Yasuda; Hisao Ogawa; Shokei Kim-Mitsuyama

doi:10.1371/journal.pone.0039162

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Peer-reviewed

Research Article

Calcium Channel Blockers, More than Diuretics, Enhance Vascular Protective Effects of Angiotensin Receptor Blockers in Salt-Loaded Hypertensive Rats

Eiichiro Yamamoto,

Affiliations Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan, Department of Cardiovascular Medicine, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Keiichiro Kataoka,

Affiliation Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Yi-Fei Dong,

Affiliations Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan, Department of Cardiovascular Medicine, Second Affiliated Hospital, Nanchang University, Nanchang, China
⨯
Nobutaka Koibuchi,

Affiliation Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Kensuke Toyama,

Affiliation Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Daisuke Sueta,

Affiliation Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Tetsuji Katayama,

Affiliation Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Osamu Yasuda,

Affiliation Department of Cardiovascular Clinical and Translational Research, Kumamoto University Hospital, Kumamoto, Japan
⨯
Hisao Ogawa,

Affiliation Department of Cardiovascular Medicine, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯
Shokei Kim-Mitsuyama

* E-mail: kimmitsu@gpo.kumamoto-u.ac.jp

Affiliation Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
⨯

Calcium Channel Blockers, More than Diuretics, Enhance Vascular Protective Effects of Angiotensin Receptor Blockers in Salt-Loaded Hypertensive Rats

Eiichiro Yamamoto,
Keiichiro Kataoka,
Yi-Fei Dong,
Nobutaka Koibuchi,
Kensuke Toyama,
Daisuke Sueta,
Tetsuji Katayama,
Osamu Yasuda,
Hisao Ogawa,
Shokei Kim-Mitsuyama

Published: June 14, 2012
https://doi.org/10.1371/journal.pone.0039162

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