TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration

Sarah Nicklas; Anthony Otto; Xiaoli Wu; Pamela Miller; Sandra Stelzer; Yefei Wen; Shihuan Kuang; Klaus Wrogemann; Ketan Patel; Hao Ding; Jens C. Schwamborn

doi:10.1371/journal.pone.0030445

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Open Access

Peer-reviewed

Research Article

TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration

Sarah Nicklas ,

Contributed equally to this work with: Sarah Nicklas, Anthony Otto

Affiliation Westfälische Wilhelms-Universität Münster, Zentrum für Molekularbiologie der Entzündung, Institute of Cell Biology, Stem Cell Biology and Regeneration Group, Münster, Germany
⨯
Anthony Otto ,

Contributed equally to this work with: Sarah Nicklas, Anthony Otto

Affiliation School of Biological Sciences, University of Reading, Whiteknights Campus, Reading, United Kingdom
⨯
Xiaoli Wu,

Affiliation Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
⨯
Pamela Miller,

Affiliation Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
⨯
Sandra Stelzer,

Affiliation Westfälische Wilhelms-Universität Münster, Zentrum für Molekularbiologie der Entzündung, Institute of Cell Biology, Stem Cell Biology and Regeneration Group, Münster, Germany
⨯
Yefei Wen,

Affiliation Department of Animal Sciences, Purdue University, West Lafayette, Indiana, United States of America
⨯
Shihuan Kuang,

Affiliation Department of Animal Sciences, Purdue University, West Lafayette, Indiana, United States of America
⨯
Klaus Wrogemann,

Affiliation Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
⨯
Ketan Patel,

Affiliation School of Biological Sciences, University of Reading, Whiteknights Campus, Reading, United Kingdom
⨯
Hao Ding ,

* E-mail: dingh@cc.umanitoba.ca (HD); jschwamb@uni-muenster.de (JS)

Affiliation Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
⨯
Jens C. Schwamborn

* E-mail: dingh@cc.umanitoba.ca (HD); jschwamb@uni-muenster.de (JS)

Affiliation Westfälische Wilhelms-Universität Münster, Zentrum für Molekularbiologie der Entzündung, Institute of Cell Biology, Stem Cell Biology and Regeneration Group, Münster, Germany
⨯

TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration

Sarah Nicklas,
Anthony Otto,
Xiaoli Wu,
Pamela Miller,
Sandra Stelzer,
Yefei Wen,
Shihuan Kuang,
Klaus Wrogemann,
Ketan Patel,
Hao Ding

Published: January 27, 2012
https://doi.org/10.1371/journal.pone.0030445

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Muscle regeneration
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Skeletal muscles
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Cell differentiation
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Muscle cells
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Myoblasts
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