The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection

Laura Bavagnoli; William G. Dundon; Anna Garbelli; Bianca Zecchin; Adelaide Milani; Geetha Parakkal; Fausto Baldanti; Stefania Paolucci; Romain Volmer; Yizeng Tu; Chuanyue Wu; Ilaria Capua; Giovanni Maga

doi:10.1371/journal.pone.0027789

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Peer-reviewed

Research Article

The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection

Laura Bavagnoli,

Affiliation Institute of Molecular Genetics National Research Council, Pavia, Italy
⨯
William G. Dundon,

Affiliation World Organization for Animal Health, Food and Agriculture Organization and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy
⨯
Anna Garbelli,

Affiliation Institute of Molecular Genetics National Research Council, Pavia, Italy
⨯
Bianca Zecchin,

Affiliation World Organization for Animal Health, Food and Agriculture Organization and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy
⨯
Adelaide Milani,

Affiliation World Organization for Animal Health, Food and Agriculture Organization and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy
⨯
Geetha Parakkal,

Affiliation Institute of Molecular Genetics National Research Council, Pavia, Italy
⨯
Fausto Baldanti,

Affiliation Molecular Virology Unit, Virology and Microbiology, Fondazione Istituto Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo, Pavia, Italy
⨯
Stefania Paolucci,

Affiliation Molecular Virology Unit, Virology and Microbiology, Fondazione Istituto Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo, Pavia, Italy
⨯
Romain Volmer,

Affiliation Université de Toulouse, Institut National Polytechnique, Ecole Nationale de Veterinaire, Unitè Mixte de Recherche 1225, Interactions Hotes-Agents Pathogènes, Toulouse, France
⨯
Yizeng Tu,

Affiliation Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Chuanyue Wu,

Affiliation Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Ilaria Capua,

Affiliation World Organization for Animal Health, Food and Agriculture Organization and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy
⨯
Giovanni Maga

* E-mail: maga@igm.cnr.it

Affiliation Institute of Molecular Genetics National Research Council, Pavia, Italy
⨯

The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection

Laura Bavagnoli,
William G. Dundon,
Anna Garbelli,
Bianca Zecchin,
Adelaide Milani,
Geetha Parakkal,
Fausto Baldanti,
Stefania Paolucci,
Romain Volmer,
Yizeng Tu

Published: November 14, 2011
https://doi.org/10.1371/journal.pone.0027789

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