A Point Mutation in Translation Initiation Factor eIF2B Leads to Function- and Time-Specific Changes in Brain Gene Expression

Open Access

Peer-reviewed

Research Article

Liraz Marom,

Affiliation Department of Cell Research and Immunology, George S. Wise Faculty of Life Science, Tel Aviv University, Tel Aviv, Israel
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Igor Ulitsky,

Current address: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Affiliation Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
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Yuval Cabilly,

Affiliation Department of Cell Research and Immunology, George S. Wise Faculty of Life Science, Tel Aviv University, Tel Aviv, Israel
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Ron Shamir,

Affiliation Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
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Orna Elroy-Stein

* E-mail: ornaes@tauex.tau.ac.il

Affiliations Department of Cell Research and Immunology, George S. Wise Faculty of Life Science, Tel Aviv University, Tel Aviv, Israel, Interdisciplinary School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
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Gene expression
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Mouse models
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Point mutation
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Brain development
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Astrocytes
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Central nervous system
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Cerebrum
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Translation initiation
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