Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

Justin D. Lathia; Joseph Gallagher; Jay T. Myers; Meizhang Li; Amit Vasanji; Roger E. McLendon; Anita B. Hjelmeland; Alex Y. Huang; Jeremy N. Rich

doi:10.1371/journal.pone.0024807

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Open Access

Peer-reviewed

Research Article

Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

Justin D. Lathia ,

* E-mail: lathiaj@ccf.org (JDL); richj@ccf.org (JNR)

Affiliation Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Joseph Gallagher,

Affiliation Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Jay T. Myers,

Affiliation Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
⨯
Meizhang Li,

Affiliation Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Amit Vasanji,

Current address: ImageIQ, Cleveland, Ohio, United States of America

Affiliation Image Processing Core, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Roger E. McLendon,

Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Anita B. Hjelmeland,

Affiliations Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Molecular Medicine Program, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
⨯
Alex Y. Huang,

Affiliation Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
⨯
Jeremy N. Rich

* E-mail: lathiaj@ccf.org (JDL); richj@ccf.org (JNR)

Affiliations Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Molecular Medicine Program, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
⨯

Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

Justin D. Lathia,
Joseph Gallagher,
Jay T. Myers,
Meizhang Li,
Amit Vasanji,
Roger E. McLendon,
Anita B. Hjelmeland,
Alex Y. Huang,
Jeremy N. Rich

Published: September 22, 2011
https://doi.org/10.1371/journal.pone.0024807

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