Spontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy

Open Access

Peer-reviewed

Research Article

Caroline Colijn,

Affiliation Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom
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Ted Cohen ,

* E-mail: tcohen@hsph.harvard.edu

Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Division of Global Health Equity, Harvard Medical School, Boston, Massachusetts, United States of America
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Ayalvadi Ganesh,

Affiliation School of Mathematics, University of Bristol, Bristol, United Kingdom
⨯
Megan Murray

Affiliation Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯

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Tuberculosis
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Antibiotic resistance
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Extensively drug-resistant tuberculosis
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Mycobacterium tuberculosis
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Drug therapy
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Microbial mutation
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Evolutionary emergence
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Drug administration
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