Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation of Targets in the Mammalian Inner Ear

Tal Elkan-Miller; Igor Ulitsky; Ronna Hertzano; Anya Rudnicki; Amiel A. Dror; Danielle R. Lenz; Ran Elkon; Martin Irmler; Johannes Beckers; Ron Shamir; Karen B. Avraham

doi:10.1371/journal.pone.0018195

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Open Access

Peer-reviewed

Research Article

Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation of Targets in the Mammalian Inner Ear

Tal Elkan-Miller,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Igor Ulitsky,

Current address: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Affiliation Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
⨯
Ronna Hertzano,

Current address: Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Anya Rudnicki,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Amiel A. Dror,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Danielle R. Lenz,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Ran Elkon,

Current address: Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Martin Irmler,

Affiliation Helmholtz Centre Munich, German Research Center for Environmental Health (GmbH), Institute of Experimental Genetics, Neuherberg/Munich, Germany
⨯
Johannes Beckers,

Affiliations Helmholtz Centre Munich, German Research Center for Environmental Health (GmbH), Institute of Experimental Genetics, Neuherberg/Munich, Germany, Technical University Munich, Center of Life and Food Sciences Weihenstephan, Freising, Germany
⨯
Ron Shamir,

Affiliation Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
⨯
Karen B. Avraham

* E-mail: karena@post.tau.ac.il

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯

Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation of Targets in the Mammalian Inner Ear

Tal Elkan-Miller,
Igor Ulitsky,
Ronna Hertzano,
Anya Rudnicki,
Amiel A. Dror,
Danielle R. Lenz,
Ran Elkon,
Martin Irmler,
Johannes Beckers,
Ron Shamir

Published: April 5, 2011
https://doi.org/10.1371/journal.pone.0018195

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MicroRNAs
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Inner ear
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Cochlea
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Gene expression
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Protein expression
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Transfection
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